Forschungsschwerpunkt Translationale Neurowissenschaften Mainz

Cognitive Neurology

Research group „Cognitive Neurology”

Our main research focus is lesion studies in stroke patients with resulting anosognosia as well as with central-vestibular and cognitive impairments. By employing state-of-the-art lesion methods we showed that the right posterior insula is remarkably often affected in stroke patients with anosognosia. We could show recently, that the right posterior insular cortex plays an important role in motion perception as well as in body perception. Further, 92% of the patients suffering from asomatognosia/ somatoparaphrenia also had anosognosia for hemiparesis. This implies a behavioral and anatomical relationship between motion perception and body perception. Our results corroborate earlier studies and case descriptions and support the interoceptive model of the insular cortex and its impact on body- and motion perception. Within a BMBF funded research collaboration we could show that the tilt of the subjective visual vertical (SVV, a sign of vestibular otolith dysfunction) is associated with the insular cortex.

 

Head of group:

Dr. med. B. Baier

 

Team members:

cand. med. Caroline Heinze

cand. med. Vinzenz Fleischer

cand. med. Clarissa Eifller

Dipl.-Psych. Janine Wilting

 

Selected Publications:

1. Baier B, Kleinschmidt  A, Müller NG. Cross-Modal Processing in Early Visual and Auditory Cortices depends on Expected Statistical Relationship of Multisensory Information. Journal of Neuroscience 2006;47:12260-12265.

2. Baier B, Bense S, Dieterich M. Are signs of ocular tilt reaction in patients with cerebellar lesions mediated by the dentate nucleus? Brain 2008;131:1445-1454.

 3. Baier B, Stoeter P, Dieterich M. Anatomical correlates of ocular motor deficits in cerebellar lesions. Brain 2009;132:2114-24.

 4. Baier B, Dieterich M, Stoeter P, Birklein F, Müller NG. Anatomical correlate of impaired covert visual attentional processes in patients with cerebellar lesions. Journal of Neuroscience 2010;30:3770-6.

 5. Baier B, Karnath HO, Dieterich M, Birklein F, Heinze C, Müller NG. Keeping memory clear and stable – the contribution of human basal ganglia and prefrontal cortex to working memory. Journal of Neuroscience 2010;30:9788-92.

 

 

News

14. September 2017
NIC meeting
Christian Paret (Central Institute of Mental Health, Mannheim) will give a talk on “Real-time fMRI neurofeedback from the amygdala: Feasibility, clinical application and brain mechanisms” in the NIC meeting on Thursday, September 14th....more
24. August 2017
NIC meeting
Dr. Til Ole Bergmann (University of Tübingen) will be guest speaker in the NIC meeting on Thursday, August 24th. His talk: “On the function of neuronal oscillations – insights from transcranial brain stimulation and multimodal imaging” will be at noon in the seminar room in building 701....more
13. July 2017
NIC meeting
Philipp Horstmann (Psychiatry, Mainz) will present the current status of the MRI study investigating the influence of prg-1 (plasticity related gene) genotype on brain morphology and function in the NIC meeting on July 13th. The NIC meetings starts at 12:00 in the seminar room in building 701!...more